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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
38.79
Human Site:
T270
Identified Species:
60.95
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
T270
R
D
I
P
L
G
A
T
V
R
N
E
M
D
S
Chimpanzee
Pan troglodytes
XP_510014
764
85553
T359
R
D
I
P
L
G
A
T
V
R
N
E
M
D
S
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
T269
R
D
I
P
L
G
A
T
V
R
N
E
M
D
S
Dog
Lupus familis
XP_547862
675
77214
T270
R
D
I
P
L
G
A
T
V
R
N
E
M
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
T270
R
D
I
P
L
G
A
T
V
R
N
E
M
D
S
Rat
Rattus norvegicus
Q5U2Y3
576
65604
I233
S
K
E
G
K
I
F
I
K
A
L
F
D
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
T270
R
D
I
P
L
G
A
T
V
R
N
E
M
D
S
Chicken
Gallus gallus
Q5ZJ00
468
52501
S128
E
I
N
G
Q
S
V
S
N
H
S
V
D
Q
L
Frog
Xenopus laevis
NP_001085267
675
76810
T270
R
D
I
P
L
G
A
T
V
R
N
D
G
D
S
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
T272
K
D
I
P
L
G
A
T
V
R
N
D
M
D
S
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
V127
A
E
I
N
G
K
S
V
A
N
Q
T
V
D
Q
Fruit Fly
Dros. melanogaster
Q24210
898
100893
L510
D
E
P
M
G
I
T
L
K
M
T
E
D
G
R
Honey Bee
Apis mellifera
XP_393395
1033
115664
T608
T
N
E
P
L
G
A
T
V
R
N
E
G
D
A
Nematode Worm
Caenorhab. elegans
P54936
961
108794
L561
Q
E
P
M
G
I
T
L
K
V
N
E
D
G
R
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
T564
T
G
E
P
L
G
A
T
I
L
N
E
N
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
0
86.6
86.6
13.3
6.6
66.6
13.3
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
100
13.3
93.3
100
33.3
13.3
80
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
67
0
7
7
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
54
0
0
0
0
0
0
0
0
0
14
27
67
7
% D
% Glu:
7
20
20
0
0
0
0
0
0
0
0
67
0
7
0
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% F
% Gly:
0
7
0
14
20
67
0
0
0
0
0
0
14
14
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
7
60
0
0
20
0
7
7
0
0
0
0
0
0
% I
% Lys:
7
7
0
0
7
7
0
0
20
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
67
0
0
14
0
7
7
0
0
0
7
% L
% Met:
0
0
0
14
0
0
0
0
0
7
0
0
47
0
0
% M
% Asn:
0
7
7
7
0
0
0
0
7
7
74
0
7
0
0
% N
% Pro:
0
0
14
67
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
7
0
0
0
0
0
7
0
0
7
7
% Q
% Arg:
47
0
0
0
0
0
0
0
0
60
0
0
0
0
14
% R
% Ser:
7
0
0
0
0
7
7
7
0
0
7
0
0
0
60
% S
% Thr:
14
0
0
0
0
0
14
67
0
0
7
7
0
0
0
% T
% Val:
0
0
0
0
0
0
7
7
60
7
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _